CONSTRUCTION OF STORE-OPERATED CALCIUM ENTRY-RELATED GENE SIGNATURE FOR PREDICTING PROGNOSIS AND INDICATES IMMUNE MICROENVIRONMENT INFILTRATION IN STOMACH ADENOCARCINOMAS

Abstract Gastric adenocarcinoma (STAD) is the most prevalent malignancy of the human digestive system and the fourth leading cause of cancer-related death.Calcium pools, especially Ca2+ entry (SOCE) for storage operations, play a crucial role in maintaining intracellular and extracellular calcium balance, influencing cell activity, and facilitating

To avoid crowd evacuation simulations depending on 2D environments and real data, we propose a framework for crowd evacuation modeling and simulation by applying deep reinforcement learning (DRL) and 3D physical environments (3DPEs).In 3DPEs, we construct simulation scenarios from the aspects of geometry, semantics and physics, which include the en

Abstract Background The liver is responsible for a range of functions in vertebrates, such as metabolism and immunity.In malaria, the liver plays a crucial role in the interaction between the parasite and host.Although malarial hepatitis is a common clinical complication of severe malaria, other malaria-related liver changes have been overlooked du

Originally the concept of CSR in developed countries is MUSCLE MIST voluntary (voluntary based).Otherwise, in IndonesiaCSR is developed on the basis of legal obligation (mandatory based).Legal norms which expressly stipulatelegal obligation for the company to implement Corporate Social Responsibility (CSR) is the Law 40 /2007 onLimited Liability Co

African horse sickness is a devastating disease that causes great suffering and many fatalities amongst horses Ophthalmic in sub-Saharan Africa.It is caused by nine different serotypes of the orbivirus African horse sickness virus (AHSV) and it is spread by Culicoid midges.The disease has significant economic consequences for the equine industry bo